Mystérieuses hépatites chez des enfants. Deux nouvelles études avancent une explication

Deux études scientifiques brought on Monday July 25 a nouvel éclairage sur de mystérieux cas d’hépatites, de graves inflammations du foie, ayant touché de très jeunes enfants dans de nombreux pays ces derniers mois, mais restant so far unexpliqués.

A little over 1,000 cases have been recorded in 35 countries, according to the World Health Organization (WHO), and 22 deaths. The majority of children affected are under six years old, and about 5% of the two have received a foie graffe.

The two studies, which have not yet been peer-reviewed, concluded that an infection with Covid-19 was not responsible. Le coronavirus was not detected in foie des enfants malades studiés, and the proportion of those who presented antibodies against Covid-19 was similar to that of children not affected with these hepatitises.

A deux virus co-infection

Conduites respectively par des scientifiques en Écosse et en Angleterre, ces études pointent ainsi du doigt un autre culpable: a common virus called AAV2 (adéno-associé virus 2), detected at des niveaux eléfêt chez les enfants malades. What virus is not normally known to cause disease.

Il ne peut se replica seul, et a besoin pour cela d’un autre virus, an adenovirus, ou more rarely le virus de l’herpès (HHV6).

Les chercheurs pensent que la co-infection de deux viruses (AAV2 and an adenovirus, or le HHV6) is currently the best explanation for these cases of hepatitis.

Encore des zones d’ombre

Je pense qu’il s’agit d’une explication plausible pour ces cascommented in a statement Deirdre Kelly, professeur en hépatologie pédiatrique à l’université de Birmingham, and n’étant pas implicie dans ces études. Co-infection appears to play a key role.

More about us always understand why certain children have developed into graves of the disease necessitating une greffe. Could a co-infection with an additional virus be a possibility?she added.

Les scientifiques do not understand more clearly pourquoi ces cas appareilence precis maintenant. One hypothesis is that the confinements linked to the coronavirus had an influence, for example in changing the usual circulation of other viruses, or in empêchant les children to create certain defenses that face the viruses that were less confronted.

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