Study conducted by Angers University Hospital confirms the usefulness of vitamin D against Covid-19

The track of vitamin D, against Covid-19, is out of nowhere. Already in January 2021, 73 experts and six learned societies, gathered around Prof. Cédric Annweiler, head of the geriatrics department at the University Hospital of Angers (Maine-et-Loire), and Prof. Jean-Claude Souberbielle, of the Necker Hospital in Paris, highlighted its effectiveness in the fight against the virus.

A new study, called COVIT-TRIAL and published in the May 31 issue of the scientific journal Plos Medicine, brings an extra stone to the building, and confirms the usefulness of vitamin D, in addition to other treatment standards.

“Very high level of evidence”

Initiated by Prof. Annweiler and piloted by the Angevin University Hospital Center, the last time “It shows, with a very high level of evidence, the interest of a strong dose of vitamin D, administered within 72 hours of diagnosis by Covid-19, to frail elderly people who have contracted the infection.”

Professor Cédric Annweiler, Head of the Geriatrics Department at the Angers University Hospital. | CATHERINE JOUANNET

Between April and December 2020, 260 patients were admitted to nine French hospitals and their Ehpads. It was made, as Prof Annweiler points out, from “Patients aged 65 years and over with Covid-19 with unfavorable developmental criteria”, et “Covid-19 patients aged 75 years and older without any other risk factor”.

Two groups, two different doses

They were randomly divided into two groups. One who receives a high dose of vitamin D within 72 hours of diagnosis; the other receiving a much lower dose, always within the same time frame.

Balance sheet: “Take a high dose of vitamin D. […] resulted in a significant and statistically significant reduction in the risk of death on the sixth day after starting treatment. » The authors of the study therefore recommend reaching “Satisfactory vitamin D status in the elderly with Covid-19 as soon as possible, with high-dose supplementation as soon as it is diagnosed.”

Limits to benefits

However, if you have been registered for 14 days, the benefit is no longer noticed after 28 days. The study authors suggest studying the effect of regular vitamin D supplementation after the initial high dose. At the same time, it should be noted that the subject of the study was not a possible preventive effect of vitamin D against severe symptoms of Covid-19. Useful, however, vitamin D is not a panacea.

Study conducted by Angers University Hospital confirms the usefulness of vitamin D against Covid-19

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